How-To Guides#

Task-oriented guides for common workflows.

Spatial Coherence Workflows (v1.0.0)#

Select Guides from Stable Regions#

Use spatial coherence to select CRISPR guides from reliable regions.

Select Guides from Stable Regions

Analyze Deep Mutational Scanning Data#

Process DMS data from MaveDB or custom experiments.

Analyze Deep Mutational Scanning Data

Guide Selection Workflows#

Filter Guides by Coherence#

Select guides using coherence thresholds and evidence levels.

Filter Guides by Coherence

Compare CRISPR Modalities#

Choose between CRISPRa, CRISPRi, knockout, and editing approaches.

Compare CRISPR Modalities

Therapeutic Workflows#

Optimize Therapeutic Dose#

Find the minimum effective dose for gene therapy.

Optimize Therapeutic Dose

Batch Process Targets#

Process multiple target genes efficiently.

Batch Process Targets